An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer
Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai […]
Recovering Gene Interactions from Single-Cell Data Using Data Diffusion
van Dijk D, Sharma R, Nainys J, Yim K, Kathail P, Carr AJ, Burdziak C, Moon KR, Chaffer CL, Pattabiraman […]
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells
Bierie B, Pierce SE, Kroeger C, Stover DG, Pattabiraman DR, Thiru P, Liu Donaher J, Reinhardt F, Chaffer CL, Keckesova […]
Medibank website: New breakthroughs in breast cancer research
Leading scientists from the Garvan Institute of Medical Research share the latest developments. “My research focuses on ‘cell plasticity’, the […]
EMT, cell plasticity and metastasis
Chaffer CL, San Juan BP, Lim E, Weinberg RA. (2016) EMT, cell plasticity and metastasis. Cancer Metastasis Rev. 35(4):645-654 PMID: […]
Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
Katajisto P, Döhla J, Chaffer CL, Pentinmikko N, Marjanovic ND, Iqbal S, Zoncu R, Chen W, Weinberg RA, Sabatini DM. […]
Poised with purpose: cell plasticity enhances tumorigenicity
Marjanovic ND, Weinberg RA, Chaffer CL. (2013). Poised with purpose: cell plasticity enhances tumorigenicity. Cell Cycle. 12(17):2713-4 PMID: 23966153 PMCID: […]
That’s not supposed to happen…
Essay on Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Read the full essay.
Poised chromatin at the ZEB1 promoter enables cell plasticity and enhances tumorigenicity
Chaffer CL, Marjanovic ND, Lee TI, Bell G, Kleer CG, Reinhardt F, D’Alessio AC, Young RA, Weinberg RA. (2013) Poised […]
Formation and maintenance of mesenchymal and stem-cell states in the breast by paracrine and autocrine signals
Scheel C, Ng Eaton E, Li SHJ, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Richardson AL, Weinberg […]