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An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

July 4, 2018February 4, 2019 Admin

Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai […]

Publications

Recovering Gene Interactions from Single-Cell Data Using Data Diffusion

July 3, 2018February 3, 2019 Admin

van Dijk D, Sharma R, Nainys J, Yim K, Kathail P, Carr AJ, Burdziak C, Moon KR, Chaffer CL, Pattabiraman […]

Publications

Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells

March 21, 2017January 28, 2019 Admin

Bierie B, Pierce SE, Kroeger C, Stover DG, Pattabiraman DR, Thiru P, Liu Donaher J, Reinhardt F, Chaffer CL, Keckesova […]

Publications

Medibank website: New breakthroughs in breast cancer research

March 8, 2017January 28, 2019 Admin

Leading scientists from the Garvan Institute of Medical Research share the latest developments. “My research focuses on ‘cell plasticity’, the […]

News

EMT, cell plasticity and metastasis

November 22, 2016January 28, 2019 Admin

Chaffer CL, San Juan BP, Lim E, Weinberg RA. (2016) EMT, cell plasticity and metastasis. Cancer Metastasis Rev. 35(4):645-654 PMID: […]

Publications

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

April 17, 2015January 28, 2019 Admin

Katajisto P, Döhla J, Chaffer CL, Pentinmikko N, Marjanovic ND, Iqbal S, Zoncu R, Chen W, Weinberg RA, Sabatini DM. […]

Publications

Poised with purpose: cell plasticity enhances tumorigenicity

September 1, 2013January 28, 2019 Admin

Marjanovic ND, Weinberg RA, Chaffer CL. (2013). Poised with purpose: cell plasticity enhances tumorigenicity. Cell Cycle. 12(17):2713-4 PMID: 23966153 PMCID: […]

Publications

That’s not supposed to happen…

July 17, 2013January 28, 2019 Admin

Essay on Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Read the full essay.

News

Poised chromatin at the ZEB1 promoter enables cell plasticity and enhances tumorigenicity

July 3, 2013January 28, 2019 Admin

Chaffer CL, Marjanovic ND, Lee TI, Bell G, Kleer CG, Reinhardt F, D’Alessio AC, Young RA, Weinberg RA. (2013) Poised […]

Publications

Formation and maintenance of mesenchymal and stem-cell states in the breast by paracrine and autocrine signals

June 10, 2011January 28, 2019 Admin

Scheel C, Ng Eaton E, Li SHJ, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Richardson AL, Weinberg […]

Publications

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